il 1r antibody Search Results


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Differentially expressed genes.
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Differentially expressed genes.
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Differentially expressed genes.
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Differentially expressed genes.
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Differentially expressed genes.
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Differentially expressed genes.
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Differentially expressed genes.
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Differentially expressed genes.
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Differentially expressed genes.
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Differentially expressed genes.
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Image Search Results


Differentially expressed genes.

Journal: Computational and Structural Biotechnology Journal

Article Title: Identification of potential diagnostic and prognostic biomarkers for sepsis based on machine learning

doi: 10.1016/j.csbj.2023.03.034

Figure Lengend Snippet: Differentially expressed genes.

Article Snippet: Western blotting Western blotting was performed as per standard protocols using primary antibodies for YOD1 (25370-1-AP, Protein Tech, Wuhan, China), GADD45A (A11768, ABclonal, Wuhan, China), BCL11B (A19804, ABclonal, Wuhan, China), IL1R2 (60262-1-Ig, ProteinTech, Wuhan, China) and GAPDH (60004-1-Ig, ProteinTech, Wuhan, China), and an electrochemiluminescence detection system (Tanon, China).

Techniques:

Expression analysis of the 11 candidate DEGs in the GSE65682 and GSE134347 datasets between sepsis and healthy control groups. The relative expression levels of (A) YOD1, (B) GADD45A, (C) BCL11B, (D) IL1R2, (E) UGCG, (F) TLR5, (G) S100A12, (H) ITK, (I) HP, (J) CCR7 and (K) C19orf59 mRNAs are shown.

Journal: Computational and Structural Biotechnology Journal

Article Title: Identification of potential diagnostic and prognostic biomarkers for sepsis based on machine learning

doi: 10.1016/j.csbj.2023.03.034

Figure Lengend Snippet: Expression analysis of the 11 candidate DEGs in the GSE65682 and GSE134347 datasets between sepsis and healthy control groups. The relative expression levels of (A) YOD1, (B) GADD45A, (C) BCL11B, (D) IL1R2, (E) UGCG, (F) TLR5, (G) S100A12, (H) ITK, (I) HP, (J) CCR7 and (K) C19orf59 mRNAs are shown.

Article Snippet: Western blotting Western blotting was performed as per standard protocols using primary antibodies for YOD1 (25370-1-AP, Protein Tech, Wuhan, China), GADD45A (A11768, ABclonal, Wuhan, China), BCL11B (A19804, ABclonal, Wuhan, China), IL1R2 (60262-1-Ig, ProteinTech, Wuhan, China) and GAPDH (60004-1-Ig, ProteinTech, Wuhan, China), and an electrochemiluminescence detection system (Tanon, China).

Techniques: Expressing, Control

Specificity at 0.85 sensitivity, PPV, and NPV of these 11 DEGs.

Journal: Computational and Structural Biotechnology Journal

Article Title: Identification of potential diagnostic and prognostic biomarkers for sepsis based on machine learning

doi: 10.1016/j.csbj.2023.03.034

Figure Lengend Snippet: Specificity at 0.85 sensitivity, PPV, and NPV of these 11 DEGs.

Article Snippet: Western blotting Western blotting was performed as per standard protocols using primary antibodies for YOD1 (25370-1-AP, Protein Tech, Wuhan, China), GADD45A (A11768, ABclonal, Wuhan, China), BCL11B (A19804, ABclonal, Wuhan, China), IL1R2 (60262-1-Ig, ProteinTech, Wuhan, China) and GAPDH (60004-1-Ig, ProteinTech, Wuhan, China), and an electrochemiluminescence detection system (Tanon, China).

Techniques:

Diagnostic value of DEGs for sepsis in the GSE65682 and GSE134347 datasets. The ROC curves of (A) YOD1, (B) GADD45A, (C) BCL11B, (D) IL1R2, (E) UGCG, (F) TLR5, (G) S100A12, (H) ITK, (I) HP, (J) CCR7 and (K) C19orf59 are shown.

Journal: Computational and Structural Biotechnology Journal

Article Title: Identification of potential diagnostic and prognostic biomarkers for sepsis based on machine learning

doi: 10.1016/j.csbj.2023.03.034

Figure Lengend Snippet: Diagnostic value of DEGs for sepsis in the GSE65682 and GSE134347 datasets. The ROC curves of (A) YOD1, (B) GADD45A, (C) BCL11B, (D) IL1R2, (E) UGCG, (F) TLR5, (G) S100A12, (H) ITK, (I) HP, (J) CCR7 and (K) C19orf59 are shown.

Article Snippet: Western blotting Western blotting was performed as per standard protocols using primary antibodies for YOD1 (25370-1-AP, Protein Tech, Wuhan, China), GADD45A (A11768, ABclonal, Wuhan, China), BCL11B (A19804, ABclonal, Wuhan, China), IL1R2 (60262-1-Ig, ProteinTech, Wuhan, China) and GAPDH (60004-1-Ig, ProteinTech, Wuhan, China), and an electrochemiluminescence detection system (Tanon, China).

Techniques: Diagnostic Assay

Prognostic value of DEGs for patients in the GSE65682 dataset. The Kaplan-Meier survival curves of the high- and low-expression groups of (A) YOD1, (B) GADD45A, (C) BCL11B, (D) IL1R2, (E) UGCG, (F) TLR5, (G) S100A12, (H) ITK, (I) HP, (J) CCR7 and (K) C19orf59 are shown.

Journal: Computational and Structural Biotechnology Journal

Article Title: Identification of potential diagnostic and prognostic biomarkers for sepsis based on machine learning

doi: 10.1016/j.csbj.2023.03.034

Figure Lengend Snippet: Prognostic value of DEGs for patients in the GSE65682 dataset. The Kaplan-Meier survival curves of the high- and low-expression groups of (A) YOD1, (B) GADD45A, (C) BCL11B, (D) IL1R2, (E) UGCG, (F) TLR5, (G) S100A12, (H) ITK, (I) HP, (J) CCR7 and (K) C19orf59 are shown.

Article Snippet: Western blotting Western blotting was performed as per standard protocols using primary antibodies for YOD1 (25370-1-AP, Protein Tech, Wuhan, China), GADD45A (A11768, ABclonal, Wuhan, China), BCL11B (A19804, ABclonal, Wuhan, China), IL1R2 (60262-1-Ig, ProteinTech, Wuhan, China) and GAPDH (60004-1-Ig, ProteinTech, Wuhan, China), and an electrochemiluminescence detection system (Tanon, China).

Techniques: Expressing

GSEA results of IL1R2. (A) T cell receptor signaling pathway. (B) Primary immunodeficiency. (C) Antigen processing and presentation. (D) Abnormal eosinophil. (E) Immunological. (F) T cell Differentiation.

Journal: Computational and Structural Biotechnology Journal

Article Title: Identification of potential diagnostic and prognostic biomarkers for sepsis based on machine learning

doi: 10.1016/j.csbj.2023.03.034

Figure Lengend Snippet: GSEA results of IL1R2. (A) T cell receptor signaling pathway. (B) Primary immunodeficiency. (C) Antigen processing and presentation. (D) Abnormal eosinophil. (E) Immunological. (F) T cell Differentiation.

Article Snippet: Western blotting Western blotting was performed as per standard protocols using primary antibodies for YOD1 (25370-1-AP, Protein Tech, Wuhan, China), GADD45A (A11768, ABclonal, Wuhan, China), BCL11B (A19804, ABclonal, Wuhan, China), IL1R2 (60262-1-Ig, ProteinTech, Wuhan, China) and GAPDH (60004-1-Ig, ProteinTech, Wuhan, China), and an electrochemiluminescence detection system (Tanon, China).

Techniques: Cell Differentiation

Validation of biomarkers in a mouse model of sepsis. (A-D) YOD1, GADD45A, BCL11B and IL1R2 mRNA levels in the heart, liver, lungs and kidneys (n = 3, compared with the Mann-Whitney test); (E-H) YOD1, GADD45A, BCL11B and IL1R2 protein levels in the heart, liver, lung and kidney tissues (n = 6, *p < 0.05, **p < 0.01, ***p < 0.001).

Journal: Computational and Structural Biotechnology Journal

Article Title: Identification of potential diagnostic and prognostic biomarkers for sepsis based on machine learning

doi: 10.1016/j.csbj.2023.03.034

Figure Lengend Snippet: Validation of biomarkers in a mouse model of sepsis. (A-D) YOD1, GADD45A, BCL11B and IL1R2 mRNA levels in the heart, liver, lungs and kidneys (n = 3, compared with the Mann-Whitney test); (E-H) YOD1, GADD45A, BCL11B and IL1R2 protein levels in the heart, liver, lung and kidney tissues (n = 6, *p < 0.05, **p < 0.01, ***p < 0.001).

Article Snippet: Western blotting Western blotting was performed as per standard protocols using primary antibodies for YOD1 (25370-1-AP, Protein Tech, Wuhan, China), GADD45A (A11768, ABclonal, Wuhan, China), BCL11B (A19804, ABclonal, Wuhan, China), IL1R2 (60262-1-Ig, ProteinTech, Wuhan, China) and GAPDH (60004-1-Ig, ProteinTech, Wuhan, China), and an electrochemiluminescence detection system (Tanon, China).

Techniques: Biomarker Discovery, MANN-WHITNEY